Drugs Details

Drugs Info of Periactin
Drugs Details
  • Drugs Type  : FDA
  • Date : 26th Jan 2015 05:04 am
  • Brand Name : Periactin
  • Generic Name : cyproheptadine (Pronunciation: SIP roe HEP ta deen)
Descriptions

Cyproheptadine (cyproheptadine hydrochloride) HCl is an antihistaminic and antiserotonergic agent.

Cyproheptadine hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) is a white to slightly yellowish, crystalline solid, which is soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform, and practically insoluble in ether. It is the sesquihydrate of 4-(5H-dibenzo[a,d] cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride. The molecular and structural formula of the anhydrous salt is:

 

Cyproheptadine HCl Structural Formula Illustration

C21H21N•HCl..................MW: 350.89

Cyproheptadine (cyproheptadine hydrochloride) HCl is available in tablets for oral administration containing 4 mg of cyproheptadine hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) . Each tablet also contains the following inactive ingredients: dibasic calcium phosphate dihydrate, magnesium stearate, microcrystalline cellulose, polyoxyl (40) stearate, purified water, sodium starch glycolate, and stearic acid.

What are the possible side effects of cyproheptadine (Periactin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking cyproheptadine and call your doctor at once if you have a serious side effect such as:

  • confusion, hallucinations, unusual thoughts or behavior;
  • seizure (convulsions);
  • ringing in your ears;
  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • easy bruising or bleeding;
  • urinating less than usual or not at all; or
  • pale or yellowed...

Read All Potential Side Effects and See Pictures of Cyproheptadine »

What are the precautions when taking cyproheptadine hydrochloride (Cyproheptadine)?

Before taking cyproheptadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart disease, high blood pressure, kidney disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that...

Read All Potential Precautions of Cyproheptadine »

This monograph has been modified to include the generic and brand name in many instances.

Indications

Perennial and seasonal allergic rhinitis

Vasomotor rhinitis

Allergic conjunctivitis due to inhalant allergens and foods

Mild, uncomplicated allergic skin manifestations of urticaria and angioedema

Amelioration of allergic reactions to blood or plasma

Cold urticaria

Dermatographism

As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.

Dosage Administration

DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT.

Each Cyproheptadine HCl Tablet contains 4 mg of cyproheptadine hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) .

Pediatric Patients

Age 2 to 6 years

The total daily dosage for pediatric patients may be calculated on the basis of body weight or body area using approximately 0.25 mg/kg/day or 8 mg per square meter of body surface (8 mg/m2).

The usual dose is 2 mg (1/2 tablet) two or three times a day, adjusted as necessry to the size and response of the patient. The dose is not to exceed 12 mg a day.

Age 7 to 14 years

The usual dose is 4 mg (1 tablet) two or three times a day, adjusted as necessary to the size and response of the patient. The dose is not to exceed 16 mg a day.

Adults

The total daily dose for adults should not exceed 0.5 mg/kg/day.

The therapeutic range is 4 mg to 20 mg a day, with the majority of patients requiring 12 mg to 16 mg a day. An occasional patient may require as much as 32 mg a day for adequate relief. It is suggested that dosage be initiated with 4 mg (1 tablet) three times a day and adjusted according to the size and response of the patient.

How Supplied

Cyproheptadine Hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) Tablets 4 mg are white, round, scored, compressed tablets, debossed "Par 043" on one side. They are available in bottles of 100 (NDC 49884-043-01), and 1000 (NDC 49884-043-10). Store at controlled room temperature, 15° to 30°C (59° to 86°F), in a well-closed container.

Manufactured by: Par Pharmaceutical Companies, Inc. Spring Valley, NY 10977. Revised: 04/08.

This monograph has been modified to include the generic and brand name in many instances.

Side Effects

Adverse reactions which have been reported with the use of antihistamines are as follows:

Central Nervous System: Sedation and sleepiness (often transient), dizziness, disturbed coordination, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paresthesias, neuritis, convulsions, euphoria, hallucination, hysteria, faintness.

Integumentary: Allergic manifestation of rash and edema, excessive perspiration, urticaria, photosensitivity.

Special Senses: Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus.

Cardiovascular: Hypotension, palpitation, tachycardia, extrasystoles, anaphylactic shock.

Hematologic: Hemolytic anemia, leukopenia, agranulocytosis, thrombocytopenia.

Digestive System: Cholestasis, heptatic failure, hepatitis, hepatic function abnormality, dryness of mouth, epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation, jaundice.

Genitourinary:Urinary frequency, difficult urination, urinary retention, early menses.

Respiratory: Dryness of nose and throat, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.

Miscellaneous: Fatigue, chills, headache, increased appetite/weight gain.

Read the Cyproheptadine (cyproheptadine hydrochloride) Side Effects Center for a complete guide to possible side effects

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Interactions

MAO Inhibitors prolong and intensify the anticholinergic effects of antihistamines.

Antihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents.

This monograph has been modified to include the generic and brand name in many instances.

Warnings

Pediatric Patients

Overdosage of antihistamines, particularly in infants and young children, may produce hallucinations, central nervous system depression, convulsions, respiratory and cardiac arrest, and death.

Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation.

CNS Depressants

Antihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents.

Activities Requiring Mental Alertness

Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.

Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients (see PRECAUTIONS, Geriatric Use).

Precautions

General

Cyproheptadine (cyproheptadine hydrochloride) has an atropine-like action and, therefore, should be used with caution in patients with:

History of bronchial asthma
Increased intraocular pressure
Hyperthyroidism
Cardiovascular disease
Hypertension

Carcinogenesis, Mutagenesis, Impairment of Fertility

Long-term carcinogenic studies have not been done with cyproheptadine (cyproheptadine hydrochloride) .

Cyproheptadine (cyproheptadine hydrochloride) had no effect on fertility in a two-litter study in rats or a two generation study in mice at about 10 times the human dose.

Cyproheptadine (cyproheptadine hydrochloride) did not produce chromosome damage in human lymphocytes or fibroblasts in-vitro; high doses (10-4M) were cytotoxic. Cyproheptadine (cyproheptadine hydrochloride) did not have any mutagenic effect in the Ames microbial mutagen test; concentrations of above 500 mcg/plate inhibited bacterial growth.

Pregnancy

Pregnancy Category B: Reproduction studies have been performed in rabbits, mice, and rats at oral or subcutaneous doses up to 32 times the maximum recommended human oral dose and have revealed no evidence of impaired fertility or harm to the fetus due to cyproheptadine (cyproheptadine hydrochloride) . Cyproheptadine (cyproheptadine hydrochloride) has been shown to be fetotoxic in rats when given by intraperitoneal injection in doses four times the maximum recommended human oral dose.Two studies in pregnant women, however, have not shown that cyproheptadine (cyproheptadine hydrochloride) increases the risk of abnormalities when administered during the first, second and third trimesters of pregnancy. No teratogenic effects were observed in any of the newborns. Nevertheless, because the studies in humans cannot rule out the possibility of harm, cyproheptadine (cyproheptadine hydrochloride) should be used during pregnancy only if clearly needed.

Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in nursing infants from cyproheptadine (cyproheptadine hydrochloride) , a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother (see CONTRAINDICATIONS).

Pediatric Use

Safety and effectiveness in pediatric patients below the age of two have not been established (see CONTRAINDICATIONS, Newborn or Premature Infants,and WARNINGS, Pediatric Patients).

Geriatric Use

Clinical studies of Cyproheptadine (cyproheptadine hydrochloride) HCl Tablets did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy (see WARNINGS, Activities Requiring Mental Alertness).

This monograph has been modified to include the generic and brand name in many instances.

OverDose

Antihistamine overdosage reactions may vary from central nervous system depression to stimulation especially in pediatric patients. Also, atropine-like signs and symptoms (dry mouth; fixed, dilated pupils; flushing, etc.) as well as gastrointestinal symptoms may occur.

If vomiting has not occurred spontaneously the patient should be induced to vomit with syrup of ipecac. If the patient is unable to vomit, perform gastric lavage followed by activated charcoal. Isotonic or 1/2 isotonic saline is the lavage of choice. Precautions against aspiration must be taken especially in infants and children.

When life threatening CNS signs and symptoms are present, intravenous physostigmine salicylate may be considered. Dosage and frequency of administration are dependent on age, clinical response, and recurrence after response. (See package circulars for physostigmine products.)

Saline cathartics, as milk of magnesia, by osmosis draw water into the bowel and, therefore, are valuable for their action in rapid dilution of bowel content. Stimulants should not be used.

Vasopressors may be used to treat hypotension.

The oral LD50 of cyproheptadine (cyproheptadine hydrochloride) is 123 mg/kg, and 295 mg/kg in the mouse and rat, respectively.

ContrainDications

Newborn or Premature Infants

This drug should not be used in newborn or premature infants.

Nursing Mothers

Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.

Other Conditions

Hypersensitivity to cyproheptadine (cyproheptadine hydrochloride) and other drugs of similar chemical structure:

Monoamine oxidase inhibitor therapy (see PRECAUTIONS: DRUG INTERACTIONS)
Angle-closure glaucoma
Stenosing peptic ulcer
Symptomatic prostatic hypertrophy
Bladder neck obstruction
Pyloroduodenal obstruction
Elderly, debilitated patients

This monograph has been modified to include the generic and brand name in many instances.

Clinical Pharamacology

Cyproheptadine (cyproheptadine hydrochloride) is a serotonin and histamine antagonist with anticholinergic and sedative effects. Antiserotonin and antihistamine drugs appear to compete with serotonin and histamine, respectively, for receptor sites.

Pharmacokinetics and Metabolism

After a single 4 mg oral dose of 14C-labelled cyproheptadine (cyproheptadine hydrochloride) HCl in normal subjects, given as tablets 2% to 20% of the radioactivity was excreted in the stools. Only about 34% of the stool radioactivity was unchanged drug, corresponding to less than 5.7% of the dose. At least 40% of the administered radioactivity was excreted in the urine. No detectable amounts of unchanged drug were present in the urine of patients on chronic 12-20 mg daily doses. The principal metabolite found in human urine has been identified as a quaternary ammonium glucuronide conjugate of cyproheptadine (cyproheptadine hydrochloride) . Elimination is diminished in renal insufficiency.

This monograph has been modified to include the generic and brand name in many instances.

Patient Information

Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation.

Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.

This monograph has been modified to include the generic and brand name in many instances.

Consumer Overview Uses

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

 

CYPROHEPTADINE - ORAL

 

(SYE-proe-HEP-ta-deen)

 

USES: Cyproheptadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. This medication also blocks another natural substance in your body (serotonin).

This medication should not be used in newborn or premature infants.

 

HOW TO USE: Take this medication by mouth with or without food as directed by your doctor, usually 2 to 3 times a day. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your age, medical condition, and response to treatment. In children, the dosage may also be based on weight and body size. Do not increase your dose or take this medication more often than directed.

Tell your doctor if your condition does not improve or if it worsens.

Consumer Overview Side Effect

SIDE EFFECTS: Drowsiness, dizziness, blurred vision, constipation, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as restlessness, confusion, hallucinations), shaking (tremor), difficulty urinating, fast/irregular heartbeat.

Get medical help right away if you have any very serious side effects, including: seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

 

Read the Cyproheptadine (cyproheptadine hydrochloride) Side Effects Center for a complete guide to possible side effects

Learn More »

PRECAUTIONS: Before taking cyproheptadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart disease, high blood pressure, kidney disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Liquid products may contain alcohol and/or sugar. Caution is advised if you have diabetes, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Children may be more sensitive to the side effects of this drug. This drug can often cause excitement in young children instead of drowsiness.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, constipation, confusion, or trouble urinating. Drowsiness, dizziness, and confusion can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Consumer Overview Missed Dose

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, other antihistamines (such as diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Do not use with any other antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray) because increased side effects may occur.

This medication may interfere with certain laboratory tests (including allergy skin testing, metyrapone test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

 

OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, seizures, widened pupils. In children, mental/mood changes (such as restlessness, irritability, hallucinations) may occur before drowsiness.

 

NOTES: Do not share this medication with others.

 

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

 

STORAGE: Store at room temperature away from light and moisture. Do not freeze the liquid form of this medication. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

 

Information last revised December 2013. Copyright(c) 2013 First Databank, Inc.

Patient Detailed Side Effect

Brand Names: Periactin

Generic Name: cyproheptadine (Pronunciation: SIP roe HEP ta deen)

  • What is cyproheptadine (Cyproheptadine)?
  • What are the possible side effects of cyproheptadine (Cyproheptadine)?
  • What is the most important information I should know about cyproheptadine (Cyproheptadine)?
  • What should I discuss with my healthcare provider before taking cyproheptadine (Cyproheptadine)?
  • How should I take cyproheptadine (Cyproheptadine)?
  • What happens if I miss a dose (Cyproheptadine)?
  • What happens if I overdose (Cyproheptadine)?
  • What should I avoid while taking cyproheptadine (Cyproheptadine)?
  • What other drugs will affect cyproheptadine (Cyproheptadine)?
  • Where can I get more information?

What is cyproheptadine (Cyproheptadine)?

Cyproheptadine an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose

Cyproheptadine is used to treat sneezing, itching, watery eyes, runny nose, and other symptoms of allergies.

Cyproheptadine may also be used for purposes not listed in this medication guide.

Cyproheptadine 4 mg-IVA

round, white, imprinted with Z 2929

What are the possible side effects of cyproheptadine (Cyproheptadine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking cyproheptadine and call your doctor at once if you have a serious side effect such as:

  • confusion, hallucinations, unusual thoughts or behavior;
  • seizure (convulsions);
  • ringing in your ears;
  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • easy bruising or bleeding;
  • urinating less than usual or not at all; or
  • pale or yellowed skin, dark colored urine, fever, or unusual weakness.

Less serious side effects may include:

  • mild drowsiness, dizziness, or spinning sensation;
  • feeling restlessness or excited (especially in children);
  • sleep problems (insomnia), tired feeling;
  • numbness or tingly feeling;
  • increased sweating or urination;
  • blurred vision;
  • appetite changes;
  • dry mouth or nose, upset stomach; or
  • nausea, diarrhea, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Cyproheptadine (cyproheptadine hydrochloride) Side Effects Center for a complete guide to possible side effects

Learn More »

What is the most important information I should know about cyproheptadine (Cyproheptadine)?

Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cold and allergy medicines in very young children.

You should not use this medication if you are allergic to cyproheptadine, or if you have narrow-angle glaucoma, a stomach ulcer or obstruction, an enlarged prostate or urination problems, if you are having an asthma attack, or if you are elderly or have a debilitating disease.

Before taking cyproheptadine, tell your doctor if you have glaucoma, a history of asthma, high blood pressure, heart disease, or an overactive thyroid.

Cyproheptadine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of cyproheptadine.

Side Effects Centers
  • Cyproheptadine

Patient Detailed How Take

What should I discuss with my healthcare provider before taking cyproheptadine (Cyproheptadine)?

Do not use cyproheptadine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not use cyproheptadine if you are allergic to it, or if you have:

  • narrow-angle glaucoma;
  • a stomach ulcer or obstruction;
  • an enlarged prostate or urination problems;
  • if you are having an asthma attack; or
  • if you are elderly or have a debilitating disease.

To make sure you can safely take cyproheptadine, tell your doctor if you have any of these other conditions:

  • glaucoma;
  • a history of asthma;
  • high blood pressure;
  • heart disease; or
  • an overactive thyroid.

FDA pregnancy category B. Cyproheptadine is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether cyproheptadine passes into breast milk, but if it does it could harm a nursing baby. Do not use this medication while you are breast-feeding a baby.

How should I take cyproheptadine (Cyproheptadine)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cold and allergy medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store at room temperature away from moisture, heat, and light.

Side Effects Centers
  • Cyproheptadine

Patient Detailed Avoid Taking

What happens if I miss a dose (Cyproheptadine)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Cyproheptadine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness, confusion, hallucinations, very dry mouth, dilated pupils, pale skin, vomiting, or fainting.

What should I avoid while taking cyproheptadine (Cyproheptadine)?

Cyproheptadine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase some of the side effects of cyproheptadine.

What other drugs will affect cyproheptadine (Cyproheptadine)?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by cyproheptadine. Tell your doctor if you regularly use any of these medicines, or any other antihistamine.

This list is not complete and other drugs may interact with cyproheptadine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about cyproheptadine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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