Drugs Details

Drugs Info of Benzamycin
Drugs Details
  • Drugs Type  : Multum
  • Date : 7th Feb 2015 02:03 am
  • Brand Name : Benzamycin
  • Generic Name : benzoyl peroxide and erythromycin topical (Pronunciation: BEN zoe ill per OX ide and er ith roe MYE sin)
Descriptions

Benzamycin® Pak contains erythromycin [(3R*, 4S*, 5S*, 6R*, 7R*, 9R*, 11R*, 12R*, 13S*, 14R*)-4-[(2,6- dideoxy-3-C-methyl-3-O-methyl-a- L-ribo-hexopyranosyl)-oxy]-14- ethyl-7,12,13-trihydroxy- 3,5,7,9,11,13-hexa-methyl-6-[ [3,4,6-trideoxy-3-(dimethylamino)-b-D- xylo-hexopyranosyl] oxy]oxacyclotetradecane-2,10- dione]. Erythromycin is a macrolide antibioticproduced from a strain of Saccharopolyspora erythraea (formerly Streptomyces erythreus). It is a base and readily forms salts with acids. Chemically, erythromycin is (C37H67NO13).  It has the following structural formula:

Erythromycin has the molecular weight of 733.94. It is a white crystalline powder and has a solubility of approximately 1 mg/mL in water and is soluble in alcohol at 25°C. Benzamycin (erythromycin) ® Pak also contains benzoyl peroxide for topical use. Benzoyl peroxide is an oxidizing agent demonstrating antibacterial activity. Chemically, benzoyl peroxide is (C14H10O4).  It has the following structural formula:

Benzoyl peroxide has the molecular weight of 242.23. It is a white granular powder and is sparingly soluble in water and alcohol and soluble in acetone, chloroformand ether. Each gram of product, as dispensed, contains 30 mg of erythromycin and 50 mg of benzoyl peroxide in a base of SD Alcohol 40B, purified water, hydroxypropyl cellulose, carbomer 934, sodium hydroxide, dioctyl sodium sulfosuccinate 75%. Each Benzamycin (erythromycin) ® Pak contains 0.8 grams of product.

 

What are the possible side effects of benzoyl peroxide and erythromycin topical (Benzamycin)?

Serious side effects are not likely to occur. Stop using benzoyl peroxide and erythromycin topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives).

You may experience some skin burning, stinging, tingling, itching, redness, dryness, peeling, or irritation while using benzoyl peroxide topical. If these side effects are excessive, apply benzoyl peroxide and erythromycin topical less often.

Side effects other than those listed...

Read All Potential Side Effects and See Pictures of Benzamycin »

What are the precautions when taking erythromycin (Benzamycin)?

Before using this product, tell your doctor or pharmacist if you are allergic to erythromycin or benzoyl peroxide; or to other macrolide antibiotics (such as azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear a hat or other protective clothing when outdoors.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription...

Read All Potential Precautions of Benzamycin »

 

This monograph has been modified to include the generic and brand name in many instances.

Indications

BENZAMYCIN (erythromycin) Topical Gel is indicated for the topical treatment ofacne vulgaris.

Dosage Administration

BENZAMYCIN (erythromycin) Topical Gel should be applied twice daily, morning and evening, or as directed by a physician, to affected areas after the skin is thoroughly washed, rinsed with warm water and gently patted dry.

How Supplied

Compounding Directions

 

SIZE 
(NET WEIGHT)
NDC 0066- BENZOYL PEROXIDE GEL ACTIVE ERYTHROMYCIN POWDER 
(IN PLASTIC VIAL)
ETHYL ALCOHOL (70%) TO BE ADDED
23.3 grams 
(as dispensed)
0510-23 20 grams 0.8 grams 3 mL
46.6 grams 
(as dispensed)
0510-46 40 grams 1.6 grams 6 mL

 

Prior to dispensing, tap vial until powder flows freely. Add indicated amount of ethyl alcohol (70%) to vial (to the mark) and immediately shake to completely dissolve erythromycin. Add this solution to gel and stir until homogeneous in appearance (1 to 1½ minutes). BENZAMYCIN (erythromycin) Topical Gel should then be stored under refrigeration. Do not freeze. Place a 3-month expiration date on the label.

NOTE: Prior to reconstitution, store at room temperature between 15° and 30°C (59° - 86°F).

After reconstitution, store under refrigeration between 2° and 8°C (36° - 46°F). Do not freeze. Keep tightly closed. Keep out of the reach of children.

Prescribing Information as of January 2003. Manufactured for Dermik Laboratories, A Division of Aventis Pharmaceuticals Inc. Berwyn, PA 19312, USA. by Aventis Pharmaceuticals Puerto Rico Inc. Manati, Puerto Rico 00674. FDA Rev date: 1/27/2003

This monograph has been modified to include the generic and brand name in many instances.

Side Effects

In controlled clinical trials, the incidence of adverse reactions associated with the use of BENZAMYCIN (erythromycin) Topical Gel was approximately 3%. These were dryness and urticarial reaction.

The following additional local adverse reactions have been reported occasionally: irritation of the skin including peeling, itching, burning sensation, erythema,inflammation of the face, eyes and nose, and irritation of the eyes. Skin discoloration, oiliness and tenderness of the skin have also been reported.

Read the Benzamycin (erythromycin) Side Effects Center for a complete guide to possible side effects

Learn More »
 
 
 

Interactions

No information provided.

This monograph has been modified to include the generic and brand name in many instances.

Warnings

Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.

Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced byClostridium difficile is one primary cause of "antibiotic-associated colitis."

After the diagnosis of pseudomembranous colitis has been established,therapeutic measures should be initiated. Mild cases of pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, proteinsupplementation and treatment with an antibacterial drug clinically effective againstC. difficile colitis.

Precautions

General: For topical use only; not for ophthalmic use. Concomitant topical acnetherapy should be used with caution because a possible cumulative irritancy effect may occur, especially with the use of peeling, desquamating or abrasive agents. If severe irritation develops, discontinue use and institute appropriate therapy. The use of antibiotic agents may be associated with the overgrowth of nonsusceptible organisms including fungi. If this occurs, discontinue use and take appropriate measures.

Avoid contact with eyes and all mucous membranes.

Carcinogenesis, Mutagenesis And Impairment Of Fertility

Data from a study using mice known to be highly susceptible to cancer suggests that benzoyl peroxide acts as a tumor promoter. The clinical significance of this is unknown.

No animal studies have been performed to evaluate the carcinogenic and mutagenic potential or effects on fertility of topical erythromycin. However, long-term (2-year) oral studies in rats with erythromycin ethylsuccinate and erythromycin base did not provide evidence of tumorigenicity. There was no apparent effect on male or female fertility in rats fed erythromycin (base) at levels up to 0.25% of diet.

Pregnancy: Teratogenic Effects: Pregnancy CATEGORY C: Animalreproduction studies have not been conducted with BENZAMYCIN (erythromycin) Topical Gel or benzoyl peroxide.

There was no evidence of teratogenicity or any other adverse effect on reproduction in female rats fed erythromycin base (up to 0.25% diet) prior to and during mating, during gestation and through weaning of two successive litters. There are no well-controlled trials in pregnant women with BENZAMYCIN (erythromycin) Topical Gel. It also is not known whether BENZAMYCIN (erythromycin) Topical Gel can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. BENZAMYCIN (erythromycin) Topical Gel should be given to a pregnant woman only if clearly needed.

Nursing Women: It is not known whether BENZAMYCIN (erythromycin) Topical Gel is excreted in human milk after topical application. However, erythromycin is excreted in human milk following oral and parenteral erythromycin administration. Therefore, caution should be exercised when erythromycin is administered to a nursing woman.

Pediatric Use: Safety and effectiveness of this product in pediatric patients below the age of 12 have not been established.

This monograph has been modified to include the generic and brand name in many instances.

 
 

OverDose

No information provided.

ContrainDications

BENZAMYCIN (erythromycin) Topical Gel is contraindicated in those individuals who have shown hypersensitivity to any of its components.

This monograph has been modified to include the generic and brand name in many instances.

Clinical Pharamacology

The exact mechanism by which erythromycin reduces lesions of acne vulgaris is not fully known; however, the effect appears to be due in part to the antibacterialactivity of the drug.

Benzoyl peroxide has a keratolytic and desquamative effect which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid.

Microbiology

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50 S ribosomal subunits, thereby inhibiting translocation of aminoacyl transfer-RNA and inhibiting polypeptide synthesis. Antagonism has been demonstrated in vitro between erythromycin, lincomycin, chloramphenicol and clindamycin.

Benzoyl peroxide is an antibacterial agent which has been shown to be effective against Propionibacterium acnes, an anaerobe found in sebaceous follicles andcomedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen.

This monograph has been modified to include the generic and brand name in many instances.

Patient Information

Patients using BENZAMYCIN (erythromycin) Topical Gel should receive the following information and instructions:

  1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, nose, mouth, and all mucous membranes.
  2. This medication should not be used for any disorder other than that for which it was prescribed.
  3. Patients should not use any other topical acne preparation unless otherwise directed by physician.
  4. Patients should report to their physician any signs of local adverse reactions.
  5. BENZAMYCIN (erythromycin) ® Topical Gel may bleach hair or colored fabric.
  6. Keep product refrigerated and discard after 3 months.

This monograph has been modified to include the generic and brand name in many instances.

Consumer Overview Uses

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

 

ERYTHROMYCIN/BENZOYL PEROXIDE - TOPICAL

 

(eh-rith-row-MY-sin/BEN-zoh-ill per-OX-ide)

 

COMMON BRAND NAME(S): Benzamycin

 

USES: This product is used to treat moderate acne. It helps to reduce the number of pimples. This medication is a combination of 2 drugs. Erythromycin works by stopping the growth of acne-causing bacteria. It belongs to a class of drugs known as macrolide antibiotics. Benzoyl peroxide also kills acne-causing bacteria and causes the top layer of skin to dry and peel off so that new skin can form. This product also contains alcohol which helps to dry extra oils from the skin.

 

HOW TO USE: Read the instructions for use that come with this product. This medication is for use only on the skin.

Before applying, wash the affected areas thoroughly, rinse with warm water, then gently pat dry. Apply a thin layer of this medication as directed by your doctor, usually twice daily (in the morning and in the evening).

If you are using the individual pouches, you must first mix the 2 medications from the separate compartments of each pouch. Mix the contents thoroughly in the palm of your hand. Apply the product immediately after mixing.

Wash your hands after using medication. Avoid getting this medication in your eyes or inside your nose, mouth, or other mucous membranes. If this occurs, rinse thoroughly with water. Do not mix or apply medication near an open flame.

Benzoyl peroxide may bleach hair or colored fabrics (such as clothing, bedding, towels). Use caution when applying this medication near the hairline.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.

Acne usually improves after a few weeks of treatment. However, it may take 2 to 3 months of continued use to notice the full benefit of this product. Tell your doctor if your condition does not improve or if it worsens.

Consumer Overview Side Effect

SIDE EFFECTS: Mild dryness and mild peeling of the top layer of skin is expected. Skin irritation, itching, burning, or redness may occur, especially at the start of treatment as your body adjusts to the medication. Eye irritation and skin discoloration may also occur. If any of these effects persist or worsen, stop using this product and tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Rarely, use of this medication for prolonged or repeated periods may result in other types of skin infections (such as fungal infections). Contact your doctor if you notice any unusual skin symptoms or if your condition does not improve.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

 

Read the Benzamycin (erythromycin) Side Effects Center for a complete guide to possible side effects

Learn More »
 

PRECAUTIONS: Before using this product, tell your doctor or pharmacist if you are allergic to erythromycin or benzoyl peroxide; or to other macrolide antibiotics (such as azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear a hat or other protective clothing when outdoors.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Consumer Overview Missed Dose

DRUG INTERACTIONS: The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Other skin products (such as cosmetics, medicated soaps, after-shave lotions, products containing alcohol) and other acne skin treatments may increase skin irritation, dryness, and peeling when used with erythromycin/benzoyl peroxide. Ask your doctor or pharmacist about what products are best for you, what products to avoid, and ways you can reduce skin irritation.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

 

OVERDOSE: This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

 

NOTES: Do not share this medication with others.

For best results, this medication is often used as part of a total skin care program. Follow your doctor's recommendations.

 

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

 

STORAGE: If you are using the individual pouches, store them at room temperature between 68-77 degrees F (20-25 degrees C).

If you are using the premixed product in the container, store in the refrigerator between 36-46 degrees F (2-8 degrees C). Do not freeze. Keep the container tightly closed. Discard after 3 months.

This medication is flammable. Keep it away from heat and open flame. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

 

Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.

 

 

Patient Detailed Side Effect

Brand Names: Benzamycin

Generic Name: benzoyl peroxide and erythromycin topical (Pronunciation: BEN zoe ill per OX ide and er ith roe MYE sin)

  • What is benzoyl peroxide and erythromycin topical (Benzamycin)?
  • What are the possible side effects of benzoyl peroxide and erythromycin topical (Benzamycin)?
  • What is the most important information I should know about benzoyl peroxide and erythromycin topical (Benzamycin)?
  • What should I discuss with my healthcare provider before using benzoyl peroxide and erythromycin topical (Benzamycin)?
  • How should I use benzoyl peroxide and erythromycin topical (Benzamycin)?
  • What happens if I miss a dose (Benzamycin)?
  • What happens if I overdose (Benzamycin)?
  • What should I avoid while taking benzoyl peroxide and erythromycin topical (Benzamycin)?
  • What other drugs will affect benzoyl peroxide and erythromycin topical (Benzamycin)?
  • Where can I get more information?

What is benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oils and dirt to be easily washed away.

Erythromycin is an antibiotic. Erythromycin topical prevents bacteria from growing on the skin.

Together, benzoyl peroxide and erythromycin are used to treat acne.

Benzoyl peroxide and erythromycin topical may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Serious side effects are not likely to occur. Stop using benzoyl peroxide and erythromycin topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives).

You may experience some skin burning, stinging, tingling, itching, redness, dryness, peeling, or irritation while using benzoyl peroxide topical. If these side effects are excessive, apply benzoyl peroxide and erythromycin topical less often.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the Benzamycin (erythromycin) Side Effects Center for a complete guide to possible side effects

Learn More »
 

What is the most important information I should know about benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Do not use benzoyl peroxide and erythromycin topical on sunburned, windburned, dry, chapped, or irritated skin or on open wounds.

Avoid abrasive, harsh, or drying soaps and cleansers while using benzoyl peroxide and erythromycin topical.

Avoid contact with clothing and hair. Benzoyl peroxide may cause bleaching.

Avoid combining PABA-containing sunscreens and benzoyl peroxide. Temporary skin discoloration may occur if they are used together.

Side Effects Centers
  • Benzamycin

Patient Detailed How Take

What should I discuss with my healthcare provider before using benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Do not use benzoyl peroxide and erythromycin topical on sunburned, windburned, dry, chapped, or irritated skin. It could make these conditions much worse. Also avoid using benzoyl peroxide and erythromycin topical on wounds or on areas of eczema. Wait until these conditions have healed before using this medication.

Do not use benzoyl peroxide and erythromycin topical during treatment with tretinoin (Retin-A). The combination could lead to severe skin irritation.

It is not known whether benzoyl peroxide and erythromycin topical will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant.

It is also not known whether benzoyl peroxide and erythromycin topical passes into breast milk. Do not use benzoyl peroxide and erythromycin topical without first talking to your doctor if you are breast-feeding a baby.

How should I use benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Use benzoyl peroxide and erythromycin topical exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before and after applying this medication.

Clean and dry the area to which you will apply the medication. Benzoyl peroxide and erythromycin topical is usually applied twice daily in the morning and evening. Follow your doctor's directions.

When applying benzoyl peroxide and erythromycin topical, avoid the eyes, the inside of the nose and mouth, the lips, and areas where the skin is broken to prevent excessive irritation. If you get medication in any of these areas, rinse it off with water.

Do not cover the affected area after applying benzoyl peroxide and erythromycin topical. Doing so could cause too much medicine to be absorbed by the body and could be harmful.

It may take several weeks or more to see the effects of this drug. Do not stop using benzoyl peroxide and erythromycin topical if you do not see results immediately.

Store benzoyl peroxide and erythromycin topical at room temperature away from moisture and heat.

Side Effects Centers
  • Benzamycin

Patient Detailed Avoid Taking

What happens if I miss a dose (Benzamycin)?

 

Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply only the next regularly scheduled dose.

What happens if I overdose (Benzamycin)?

 

An overdose of benzoyl peroxide and erythromycin topical is unlikely to occur. If you do suspect an overdose, or if benzoyl peroxide and erythromycin topical has been ingested, call a poison control center or emergency room for advice.

What should I avoid while taking benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Do not use benzoyl peroxide and erythromycin topical on sunburned, windburned, dry, chapped, or irritated skin or on open wounds.

Avoid using other topical products on the same area at the same time unless directed to do so by your doctor. They may interfere with the effects or absorption of benzoyl peroxide and erythromycin topical.

Do not cover the affected area after applying benzoyl peroxide and erythromycin topical. Doing so could cause too much medicine to be absorbed by the body and could be harmful.

Avoid using harsh, abrasive, or irritating cleansers, perfumes, or cosmetics on the affected area.

Avoid contact with clothing and hair. Benzoyl peroxide may cause bleaching.

Avoid combining PABA-containing sunscreens and benzoyl peroxide. Temporary skin discoloration may occur if they are used together.

What other drugs will affect benzoyl peroxide and erythromycin topical (Benzamycin)?

 

Do not use benzoyl peroxide and erythromycin topical during treatment with tretinoin (Retin-A). The combination could lead to severe skin irritation.

Do not use other topical prescription or over-the-counter products on the same area at the same time unless directed to do so by your doctor.

Avoid using harsh, abrasive, or irritating cleansers, perfumes, or cosmetics on the area being treated.

Drugs other than those listed here may also interact with benzoyl peroxide and erythromycin topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

 

Your pharmacist has additional information about benzoyl peroxide and erythromycin topical written for health professionals that you may read.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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